CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function

CRISPR/Cas9 editing reveals novel mechanisms of clustered microRNA regulation and function

Abstract MicroRNAs (miRNAs) are important regulators of diverse physiological and pathophysiological processes. MiRNA families and clusters are two key features in miRNA biology. Here we explore the use of CRISPR/Cas9 as a powerful tool to delineate the function and regulation of miRNA families and...

Полное описание

Библиографические подробности
Главные авторы: Lazaros Lataniotis, Andreas Albrecht, Fatma O. Kok, Clinton A. L. Monfries, Lorena Benedetti, Nathan D. Lawson, Simon M. Hughes, Kathleen Steinhofel, Manuel Mayr, Anna Zampetaki
Формат: Статья
Язык:English
Опубликовано: Nature Portfolio 2017-08-01
Серии:Scientific Reports
Online-ссылка:https://doi.org/10.1038/s41598-017-09268-0

Internet

https://doi.org/10.1038/s41598-017-09268-0

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