epiAneufinder identifies copy number alterations from single-cell ATAC-seq data

Abstract Single-cell open chromatin profiling via scATAC-seq has become a mainstream measurement of open chromatin in single-cells. Here we present epiAneufinder, an algorithm that exploits the read count information from scATAC-seq data to extract genome-wide copy number alterations (CNAs) for indi...

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Bibliographic Details
Main Authors: Akshaya Ramakrishnan, Aikaterini Symeonidi, Patrick Hanel, Katharina T. Schmid, Maria L. Richter, Michael Schubert, Maria Colomé-Tatché
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41076-1