Getting to S: CDK functions and targets on the path to cell-cycle commitment [version 1; referees: 2 approved]
How and when eukaryotic cells make the irrevocable commitment to divide remain central questions in the cell-cycle field. Parallel studies in yeast and mammalian cells seemed to suggest analogous control mechanisms operating during the G1 phase—at Start or the restriction (R) point, respectively—to...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2016-09-01
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| Series: | F1000Research |
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| Online Access: | http://f1000research.com/articles/5-2374/v1 |