Neurotrophin gene therapy for sustained neural preservation after deafness.

The cochlear implant provides auditory cues to profoundly deaf patients by electrically stimulating the residual spiral ganglion neurons. These neurons, however, undergo progressive degeneration after hearing loss, marked initially by peripheral fibre retraction and ultimately culminating in cell de...

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Bibliographic Details
Main Authors: Patrick J Atkinson, Andrew K Wise, Brianna O Flynn, Bryony A Nayagam, Clifford R Hume, Stephen J O'Leary, Robert K Shepherd, Rachael T Richardson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3524079?pdf=render