Regulation of phase separation and antiviral activity of Cactin by glycolytic enzyme PGK via phosphorylation in Drosophila

Regulation of phase separation and antiviral activity of Cactin by glycolytic enzyme PGK via phosphorylation in Drosophila

ABSTRACTLiquid–liquid phase separation (LLPS) plays a crucial role in various biological processes in eukaryotic organisms, including immune responses in mammals. However, the specific function of LLPS in immune responses in Drosophila melanogaster remains poorly understood. Cactin, a highly conserv...

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Bibliographic Details
Main Authors: Dongchao Chen, Chang Shi, Wen Xu, Qiqi Rong, Qingfa Wu
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:mBio
Subjects:
Cactin
antiviral immunity
liquid–liquid phase separation
phosphoglycerate kinase
Drosophila C virus
Drosophila melanogaster
Online Access:https://journals.asm.org/doi/10.1128/mbio.01378-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01378-23

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