Bisphenol A induces apoptosis and autophagy in murine osteocytes MLO-Y4: Involvement of ROS-mediated mTOR/ULK1 pathway

Bisphenol A induces apoptosis and autophagy in murine osteocytes MLO-Y4: Involvement of ROS-mediated mTOR/ULK1 pathway

Bisphenol A (BPA) is a widely environmental endocrine disruptor. The accumulated BPA in humans is toxic to osteoblasts and osteoclasts, but few studies focused on the effects of BPA on osteocytes, the most abundant bone cell type, contributing to the development and metabolism of bone. Here, we repo...

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Bibliographic Details
Main Authors: Yun Zhang, Ming Yan, Shumeng Kuang, Yiqiang Lou, Shouqian Wu, Yurong Li, Zihan Wang, Hongjiao Mao
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
BPA
Osteocytes
Apoptosis
Autophagy
mTOR/ULK1 pathway
ROS
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651321012318

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http://www.sciencedirect.com/science/article/pii/S0147651321012318

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