A candidate gene analysis and GWAS for genes associated with maternal nondisjunction of chromosome 21.

A candidate gene analysis and GWAS for genes associated with maternal nondisjunction of chromosome 21.

Human nondisjunction errors in oocytes are the leading cause of pregnancy loss, and for pregnancies that continue to term, the leading cause of intellectual disabilities and birth defects. For the first time, we have conducted a candidate gene and genome-wide association study to identify genes asso...

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Bibliographic Details
Main Authors: Jonathan M Chernus, Emily G Allen, Zhen Zeng, Eva R Hoffman, Terry J Hassold, Eleanor Feingold, Stephanie L Sherman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-12-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008414

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https://doi.org/10.1371/journal.pgen.1008414

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