Pan-Cancer Analysis Identifies Tumor Cell Surface Targets for CAR-T Cell Therapies and Antibody Drug Conjugates

Pan-Cancer Analysis Identifies Tumor Cell Surface Targets for CAR-T Cell Therapies and Antibody Drug Conjugates

Tumor cells can be recognized through tumor surface antigens by immune cells and antibodies, which therefore can be used as drug targets for chimeric antigen receptor-T (CAR-T) therapies and antibody drug conjugates (ADCs). In this study, we aimed to identify novel tumor-specific antigens as targets...

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Bibliographic Details
Main Authors: Xinhui Li, Jian Zhou, Weiwen Zhang, Wenhua You, Jun Wang, Linlin Zhou, Lei Liu, Wei-Wei Chen, Hanjie Li
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cancers
Subjects:
pan-cancer analysis
tumor-specific antigens (TSAs)
chimeric antigen receptor-T (CAR-T) cell
antibody drug conjugates (ADCs)
Online Access:https://www.mdpi.com/2072-6694/14/22/5674

Internet

https://www.mdpi.com/2072-6694/14/22/5674

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