Base-resolution prediction of transcription factor binding signals by a deep learning framework.

Transcription factors (TFs) play an important role in regulating gene expression, thus the identification of the sites bound by them has become a fundamental step for molecular and cellular biology. In this paper, we developed a deep learning framework leveraging existing fully convolutional neural...

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Bibliographic Details
Main Authors: Qinhu Zhang, Ying He, Siguo Wang, Zhanheng Chen, Zhenhao Guo, Zhen Cui, Qi Liu, De-Shuang Huang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1009941