Integrating single-cell and bulk RNA sequencing to predict prognosis and immunotherapy response in prostate cancer

Abstract Prostate cancer (PCa) stands as a prominent contributor to morbidity and mortality among males on a global scale. Cancer-associated fibroblasts (CAFs) are considered to be closely connected to tumour growth, invasion, and metastasis. We explored the role and characteristics of CAFs in PCa t...

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Bibliographic Details
Main Authors: Xiao Yan Wen, Ru Yi Wang, Bei Yu, Yue Yang, Jin Yang, Han Chao Zhang
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42858-9