Crosstalk between PI3K/Akt and Wnt/β-catenin pathways promote colorectal cancer progression regardless of mutational status

The PI3K/Akt and Wnt/β-catenin pathways play an important role in the acquisition of the malignant phenotype in cancer. However, there are few data regarding the role of the interplay between both pathways in colorectal cancer (CRC) progression. The mutational status and the clinicopathological char...

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Bibliographic Details
Main Authors: Cassio Dejair Fleming-de-Moraes, Murilo Ramos Rocha, Josiane Weber Tessmann, Wallace Martins de Araujo, Jose Andres Morgado-Diaz
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Cancer Biology & Therapy
Subjects:
Online Access:http://dx.doi.org/10.1080/15384047.2022.2108690