The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases

The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases

<i>Background:</i> Osteosarcoma is the most frequent form of malignant pediatric bone tumor. Despite the current therapeutic arsenal, patient life-expectancy remains low if metastases are detected at the time of diagnosis, justifying research into better knowledge at all stages of osteos...

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Bibliographic Details
Main Authors: Benjamin Navet, Kosei Ando, Jorge William Vargas-Franco, Régis Brion, Jérome Amiaud, Kanji Mori, Hideo Yagita, Christopher G. Mueller, Franck Verrecchia, Clotilde Dumars, Marie-Françoise Heymann, Dominique Heymann, Frédéric Lézot
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Cancers
Subjects:
RANKL/RANK
osteosarcoma
metastases
bone
T-lymphocyte
Online Access:https://www.mdpi.com/2072-6694/10/11/398

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https://www.mdpi.com/2072-6694/10/11/398

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