Evaluation of Piperacillin/Sulbactam, Piperacillin/Tazobactam and Cefoperazone/Sulbactam Dosages in Gram-Negative Bacterial Bloodstream Infections by Monte Carlo Simulation

Evaluation of Piperacillin/Sulbactam, Piperacillin/Tazobactam and Cefoperazone/Sulbactam Dosages in Gram-Negative Bacterial Bloodstream Infections by Monte Carlo Simulation

The optimal regimens of piperacillin/sulbactam (PIS 2:1), piperacillin/tazobactam (PTZ 8:1), and cefoperazone/sulbactam (CSL 2:1) are not well defined in patients based on renal function. This study was conducted to identify optimal regimens of BLBLIs in these patients. The antimicrobial sensitivity...

Full description

Bibliographic Details
Main Authors: Xueting Wang, Luying Xiong, Wei Yu, Chen Huang, Jinru Ji, Chaoqun Ying, Zhiying Liu, Yunbo Chen, Yonghong Xiao
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Antibiotics
Subjects:
Monte Carlo simulation
bloodstream infections
pharmacokinetics/pharmacodynamics
piperacillin/sulbactam
piperacillin/tazobactam
cefoperazone/sulbactam
Online Access:https://www.mdpi.com/2079-6382/12/2/363

Internet

https://www.mdpi.com/2079-6382/12/2/363

Similar Items