Histone Lysine Methyltransferase Wolf-Hirschhorn Syndrome Candidate 1 Is Involved in Human Carcinogenesis through Regulation of the Wnt Pathway

Histone Lysine Methyltransferase Wolf-Hirschhorn Syndrome Candidate 1 Is Involved in Human Carcinogenesis through Regulation of the Wnt Pathway

A number of histone methyltransferases have been identified and biochemically characterized, but the pathologic roles of their dysfunction in human diseases like cancer are not well understood. Here, we demonstrate that Wolf-Hirschhorn syndrome candidate 1 (WHSC1) plays important roles in human carc...

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Bibliographic Details
Main Authors: Gouji Toyokawa, Hyun-Soo Cho, Ken Masuda, Yuka Yamane, Masanori Yoshimatsu, Shinya Hayami, Masashi Takawa, Yukiko Iwai, Yataro Daigo, Eiju Tsuchiya, Tatsuhiko Tsunoda, Helen I. Field, John D. Kelly, David E. Neal, Yoshihiko Maehara, Bruce A.J. Ponder, Yusuke Nakamura, Ryuji Hamamoto
Format: Article
Language:English
Published: Elsevier 2011-10-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800771

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http://www.sciencedirect.com/science/article/pii/S1476558611800771

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