A Possible Inhibitory Role of Sialic Acid on MUC1 in Peritoneal Dissemination of Clear Cell-Type Ovarian Cancer Cells

The role of sialic acids on MUC1 in peritoneal dissemination of ovarian cancer cells was investigated. A human ovarian carcinoma cell line, ES-2, was transfected with full-length MUC1 containing 22 or 42 tandem repeats. These transfectants were less adherent to monolayers of patient-derived mesothel...

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Bibliographic Details
Main Authors: Yutaka Tamada, Hiroyuki Nomura, Daisuke Aoki, Tatsuro Irimura
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/26/19/5962