Locus-Specific Enrichment Analysis of 5-Hydroxymethylcytosine Reveals Novel Genes Associated with Breast Carcinogenesis

Locus-Specific Enrichment Analysis of 5-Hydroxymethylcytosine Reveals Novel Genes Associated with Breast Carcinogenesis

An imbalance in DNA methylation is a hallmark epigenetic alteration in cancer. The conversion of 5-methylcytosine (5-mC) to 5-hydroxymethyl cytosine (5-hmC), which causes the imbalance, results in aberrant gene expression. The precise functional role of 5-hydroxymethylcytosine in breast cancer remai...

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Bibliographic Details
Main Authors: Deepa Ramasamy, Arunagiri Kuha Deva Magendhra Rao, Meenakumari Balaiah, Arvinden Vittal Rangan, Shirley Sundersingh, Sridevi Veluswami, Rajkumar Thangarajan, Samson Mani
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
DNA methylation or 5-methylcytosine
5-hydroxymethyl cytosine
methylation imbalance
breast cancer
DMR
DhMR
Online Access:https://www.mdpi.com/2073-4409/11/19/2939

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https://www.mdpi.com/2073-4409/11/19/2939

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