Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development

Perinatal exposure to PFOS and sustained high-fat diet promote neurodevelopmental disorders via genomic reprogramming of pathways associated with neuromotor development

Perfluorooctanesulfonic acid (PFOS) is a neurotoxic widespread organic contaminant which affects several brain functions including memory, motor coordination and social activity. PFOS has the ability to traverse the placenta and the blood brain barrier (BBB) and cause weight gain in female mice. It’...

Full description

Bibliographic Details
Main Authors: Issam Hmila, Jaunetta Hill, Karim E. Shalaby, Khalid Ouararhni, Houari Abedsselem, Seyed Mohamad Sadegh Modaresi, Syed Waseem Bihaqi, Emily Marques, Anya Sondhi, Angela L. Slitt, Nasser H. Zawia
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PFOS
High fat diet
Tau pathology
Calcium pathway
MAPK pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324001453

Internet

http://www.sciencedirect.com/science/article/pii/S0147651324001453

Similar Items