Young infants display heterogeneous serological responses and extensive but reversible transcriptional changes following initial immunizations

Young infants display heterogeneous serological responses and extensive but reversible transcriptional changes following initial immunizations

Abstract Infants necessitate vaccinations to prevent life-threatening infections. Our understanding of the infant immune responses to routine vaccines remains limited. We analyzed two cohorts of 2-month-old infants before vaccination, one week, and one-month post-vaccination. We report remarkable he...

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Bibliographic Details
Main Authors: Nima Nouri, Raquel Giacomelli Cao, Eleonora Bunsow, Djamel Nehar-Belaid, Radu Marches, Zhaohui Xu, Bennett Smith, Santtu Heinonen, Sara Mertz, Amy Leber, Gaby Smits, Fiona van der Klis, Asunción Mejías, Jacques Banchereau, Virginia Pascual, Octavio Ramilo
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43758-2

Internet

https://doi.org/10.1038/s41467-023-43758-2

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