Virus identification in unknown tropical febrile illness cases using deep sequencing.

Dengue virus is an emerging infectious agent that infects an estimated 50-100 million people annually worldwide, yet current diagnostic practices cannot detect an etiologic pathogen in ∼40% of dengue-like illnesses. Metagenomic approaches to pathogen detection, such as viral microarrays and deep seq...

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Bibliographic Details
Main Authors: Nathan L Yozwiak, Peter Skewes-Cox, Mark D Stenglein, Angel Balmaseda, Eva Harris, Joseph L DeRisi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3274504?pdf=render