HSP90, as a functional target antigen of a mAb 11C9, promotes stemness and tumor progression in hepatocellular carcinoma

HSP90, as a functional target antigen of a mAb 11C9, promotes stemness and tumor progression in hepatocellular carcinoma

Abstract Background Identification of promising targeted antigens that exhibited cancer-specific expression is a crucial step in the development of novel antibody-targeted therapies. We here aimed to investigate the anti-tumor activity of a novel monoclonal antibody (mAb) 11C9 and identify the antib...

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Bibliographic Details
Main Authors: Hui-Qi Liu, Li-Xin Sun, Long Yu, Jun Liu, Li-Chao Sun, Zhi-Hua Yang, Xiong Shu, Yu-Liang Ran
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Stem Cell Research & Therapy
Subjects:
Hepatocellular carcinoma
Liver cancer
Cancer stem cells
Monoclonal antibody
Tumor-associated antigens
Stemness
Online Access:https://doi.org/10.1186/s13287-023-03453-x

Internet

https://doi.org/10.1186/s13287-023-03453-x

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