HSP90, as a functional target antigen of a mAb 11C9, promotes stemness and tumor progression in hepatocellular carcinoma
Abstract Background Identification of promising targeted antigens that exhibited cancer-specific expression is a crucial step in the development of novel antibody-targeted therapies. We here aimed to investigate the anti-tumor activity of a novel monoclonal antibody (mAb) 11C9 and identify the antib...
Main Authors: | Hui-Qi Liu, Li-Xin Sun, Long Yu, Jun Liu, Li-Chao Sun, Zhi-Hua Yang, Xiong Shu, Yu-Liang Ran |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2023-09-01
|
Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13287-023-03453-x |
Similar Items
-
The Cancer Stem Cell in Hepatocellular Carcinoma
by: Lucas-Alexander Schulte, et al.
Published: (2020-03-01) -
The mRNA Distribution of Cancer Stem Cell Marker CD90/Thy-1 Is Comparable in Hepatocellular Carcinoma of Eastern and Western Populations
by: An B. Luong, et al.
Published: (2020-12-01) -
Stemness markers in hepatocellular carcinoma of Eastern vs. Western population: Etiology matters?
by: Caecilia HC Sukowati, et al.
Published: (2024-01-01) -
Cancer Stem Cell Functions in Hepatocellular Carcinoma and Comprehensive Therapeutic Strategies
by: Yu-Chin Liu, et al.
Published: (2020-05-01) -
The stromal-tumor amplifying STC1-Notch1 feedforward signal promotes the stemness of hepatocellular carcinoma
by: Shuya Bai, et al.
Published: (2023-03-01)