Safety and Efficacy of Mek Inhibitors in the Treatment of Plexiform Neurofibromas: A Retrospective Study

Introduction Plexiform neurofibromas (PN) represent the main cause of morbidity in patients affected by Neurofibromatosis Type 1 (NF1). Until recently, surgery has been the main treatment option in these patients, but it is burdened with a low efficacy rate and a high incidence of side effects as we...

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Main Authors: Antonella Cacchione MD, Francesco Fabozzi MD, Andrea Carai MD, PhD, Giovanna Stefania Colafati MD, Giada del Baldo MD, Sabrina Rossi MD, Martino Diana MD, Giacomina Megaro MD, Giuseppe Maria Milano MD, PhD, Marina Macchiaiolo MD, Alessandro Crocoli MD, Maria Antonietta De Ioris MD, Luigi Boccuto MD, Domitilla Elena Secco MD, Mario Zama MD, Emanuele Agolini MD, Paolo Tomà, Angela Mastronuzzi MD, PhD
Format: Article
Language:English
Published: SAGE Publishing 2023-01-01
Series:Cancer Control
Online Access:https://doi.org/10.1177/10732748221144930