Effects of adrenergic-stimulated lipolysis and cytokine production on in vitro mouse adipose tissue–islet interactions
Abstract Inflammatory cytokines and non-esterified fatty acids (NEFAs) are obesity-linked factors that disturb insulin secretion. The aim of this study was to investigate whether pancreatic adipose tissue (pWAT) is able to generate a NEFA/cytokine overload within the pancreatic environment and as co...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
|
Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-18262-0 |