Effects of adrenergic-stimulated lipolysis and cytokine production on in vitro mouse adipose tissue–islet interactions

Effects of adrenergic-stimulated lipolysis and cytokine production on in vitro mouse adipose tissue–islet interactions

Abstract Inflammatory cytokines and non-esterified fatty acids (NEFAs) are obesity-linked factors that disturb insulin secretion. The aim of this study was to investigate whether pancreatic adipose tissue (pWAT) is able to generate a NEFA/cytokine overload within the pancreatic environment and as co...

Full description

Bibliographic Details
Main Authors:	Morgana Barroso Oquendo, Estela Lorza-Gil, David Juarez-Lopez, Robert Wagner, Andreas L. Birkenfeld, Susanne Ullrich, Felicia Gerst
Format:	Article
Language:	English
Published:	Nature Portfolio 2022-09-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-022-18262-0

Similar Items

Effect of beta-adrenergic stimulation on whole-body and abdominal subcutaneous adipose tissue lipolysis in lean and obese men.
by: Jocken, J, et al.
Published: (2008)

Effect of beta-adrenergic stimulation on whole-body and regional abdominal subcutaneous adipose tissue lipolysis in lean and obese men
by: Jocken, J, et al.
Published: (2007)

Stimulation of lipolysis in adipose tissue in vitro by inhibitors of lipid mobilization
by: F.P. Kupiecki, et al.
Published: (1970-01-01)

What role do fat cells play in pancreatic tissue?
by: Felicia Gerst, et al.
Published: (2019-07-01)

Growth hormone stimulates lipolysis in mice but not in adipose tissue or adipocyte culture
by: Lidan Zhao, et al.
Published: (2023-01-01)

Gluteofemoral Fat as a Determinant of Metabolic Health: Differential Adrenergic Regulation of Regional Lipolysis and Adipose Tissue Blood Flow In Vivo
by: Manolopoulos, K, et al.
Published: (2010)

Adipose retinol saturase is regulated by β-adrenergic signaling and its deletion impairs lipolysis in adipocytes and acute cold tolerance in mice
by: Chen Li, et al.
Published: (2024-01-01)

Palmitate and insulin counteract glucose-induced thioredoxin interacting protein (TXNIP) expression in insulin secreting cells via distinct mechanisms.
by: Madhura Panse, et al.
Published: (2018-01-01)

Cardiotrophin-1 stimulates lipolysis through the regulation of main adipose tissue lipases[S]
by: Miguel López-Yoldi, et al.
Published: (2014-12-01)

Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation
by: Emilio P. Mottillo, et al.
Published: (2014-11-01)

The Molecular Brakes of Adipose Tissue Lipolysis
by: Yongguo Li, et al.
Published: (2022-02-01)

Adipose METTL14‐Elicited N6‐Methyladenosine Promotes Obesity, Insulin Resistance, and NAFLD Through Suppressing β Adrenergic Signaling and Lipolysis
by: Qianqian Kang, et al.
Published: (2023-10-01)

Uninephrectomy in rats on a fixed food intake results in adipose tissue lipolysis implicating spleen cytokines.
by: Denis eArsenijevic, et al.
Published: (2015-07-01)

GPCR in Adipose Tissue Function—Focus on Lipolysis
by: Davide Malfacini, et al.
Published: (2023-02-01)

Lipolysis and lipases in white adipose tissue – An update
by: Andressa Bolsoni-Lopes, et al.

β3-Adrenergic receptors regulate human brown/beige adipocyte lipolysis and thermogenesis
by: Cheryl Cero, et al.
Published: (2021-06-01)

Lipid Profiling Reveals Browning Heterogeneity of White Adipose Tissue by Β3-Adrenergic Stimulation
by: Ping He, et al.
Published: (2019-09-01)

Pulsatile blood flow and lipolysis in human adipose tissue
by: Frayn, K, et al.
Published: (2004)

Adipose lipolysis is required for PTH-induced bone formation
by: Nathalie Alekos, et al.
Published: (2021-04-01)

Periparturient lipolysis and oxylipid biosynthesis in bovine adipose tissues.
by: G Andres Contreras, et al.
Published: (2017-01-01)

Parathyroid hormone-induced lipolysis in human adipose tissue
by: A Taniguchi, et al.
Published: (1987-05-01)

Extracellular Matrix Expression in Human Pancreatic Fat Cells of Patients with Normal Glucose Regulation, Prediabetes and Type 2 Diabetes
by: Dorothea Siegel-Axel, et al.
Published: (2023-07-01)

Estrogen-Related Receptors Mediate the Adaptive Response of Brown Adipose Tissue to Adrenergic Stimulation
by: Erin L. Brown, et al.
Published: (2018-04-01)

Inhibition of epinephrine-induced lipolysis in isolated white adipocytes of aging rabbits by increased alpha-adrenergic responsiveness.
by: M Lafontan
Published: (1979-02-01)

Electroacupuncture Stimulation Regulates Adipose Lipolysis via Catecholamine Signaling Mediated by NLRP3 Suppression in Obese Rats
by: Mengjiang Lu, et al.
Published: (2022-01-01)

Alcohol, White Adipose Tissue, and Brown Adipose Tissue: Mechanistic Links to Lipogenesis and Lipolysis
by: Qing Li, et al.
Published: (2023-06-01)

Effects of physiological hypercortisolemia on the regulation of lipolysis in subcutaneous adipose tissue.
by: Samra, J, et al.
Published: (1998)

Sympathetic neuro-adipose connections mediate leptin-driven lipolysis
by: Zeng, W, et al.
Published: (2015)

Assessment of lipolysis biomarkers in adipose tissue of patients with gastrointestinal cancer
by: Federica Tambaro, et al.
Published: (2024-01-01)

Protocol for assessing ex vivo lipolysis of murine adipose tissue
by: Debasish Roy, et al.
Published: (2022-09-01)

Suppression of adipose lipolysis by long-chain fatty acid analogs
by: Bella Kalderon, et al.
Published: (2012-05-01)

Regional variation in adipose tissue lipolysis in lean and obese men.
by: P Mauriège, et al.
Published: (1991-10-01)

Phosphorylation of Beta-3 adrenergic receptor at serine 247 by ERK MAP kinase drives lipolysis in obese adipocytes
by: Shangyu Hong, et al.
Published: (2018-06-01)

Lactiplantibacillus plantarum L67 reduces diet-induced obesity by stimulating gene programming for adipose lipolysis and energy expenditure
by: Eunjeong Hong, et al.
Published: (2024-02-01)

Failure to increase postprandial blood flow in subcutaneous adipose tissue is associated with tissue resistance to adrenergic stimulation
by: Ardilouze, J, et al.
Published: (2011)

Failure to increase postprandial blood flow in subcutaneous adipose tissue is associated with tissue resistance to adrenergic stimulation.
by: Ardilouze, J, et al.
Published: (2012)

Subcutaneous adipose tissue insulin resistance and lipolysis in patients with nonalcoholic steatohepatitis
by: Armstrong, M, et al.
Published: (2013)

Adipocyte Pseudohypoxia Suppresses Lipolysis and Facilitates Benign Adipose Tissue Expansion.
by: Michailidou, Z, et al.
Published: (2014)

Anti-Lipolysis Induced by Insulin in Diverse Pathophysiologic Conditions of Adipose Tissue
by: Zhao J, et al.
Published: (2020-05-01)

Hypoxia-Induced Adipose Lipolysis Requires Fibroblast Growth Factor 21
by: Guicheng Wu, et al.
Published: (2020-08-01)