Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity

Total Synthesis of the Natural Chalcone Lophirone E, Synthetic Studies toward Benzofuran and Indole-Based Analogues, and Investigation of Anti-Leishmanial Activity

The potential of natural and synthetic chalcones as therapeutic leads against different pathological conditions has been investigated for several years, and this class of compounds emerged as a privileged chemotype due to its interesting anti-inflammatory, antimicrobial, antiviral, and anticancer pr...

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Bibliographic Details
Main Authors: Luca Pozzetti, Roberta Ibba, Sara Rossi, Orazio Taglialatela-Scafati, Donatella Taramelli, Nicoletta Basilico, Sarah D’Alessandro, Silvia Parapini, Stefania Butini, Giuseppe Campiani, Sandra Gemma
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
chalcones
2-arylbenzofuran
2-arylindole
<i>Leishmania</i> spp.
Online Access:https://www.mdpi.com/1420-3049/27/2/463

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https://www.mdpi.com/1420-3049/27/2/463

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