Germline genetic biomarkers to stratify patients for personalized radiation treatment

Germline genetic biomarkers to stratify patients for personalized radiation treatment

Abstract Background Precision medicine incorporating genetic profiling is becoming a standard of care in medical oncology. However, in the field of radiation oncology there is limited use of genetic profiling and the impact of germline genetic biomarkers on radiosensitivity, radioresistance, or pati...

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Bibliographic Details
Main Authors: Ida Deichaite, Austin Hopper, Lena Krockenberger, Timothy J. Sears, Leisa Sutton, Xenia Ray, Andrew Sharabi, Ami Navon, Parag Sanghvi, Hannah Carter, Vitali Moiseenko
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Journal of Translational Medicine
Subjects:
Predictive biomarkers of radiation toxicity
Head and neck squamous cell carcinoma
Radiogenomics
Germline variants
TSC2
HLA-A
Online Access:https://doi.org/10.1186/s12967-022-03561-x

Internet

https://doi.org/10.1186/s12967-022-03561-x

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