52350 PKM2 mediates anti-tumor immunity and T cell dysfunction

52350 PKM2 mediates anti-tumor immunity and T cell dysfunction

ABSTRACT IMPACT: T cell dysfunction is a dominant suppressor of anti-tumor immunity, reducing immunotherapeutic efficacy and benefit to patients; our work will identify novel mediators of this process for both therapeutic potential and underlying mechanism, allowing for both potential immediate clin...

Full description

Bibliographic Details
Main Authors: Geoffrey Markowitz, Yi Ban, Michael Crowley, Diamile Tavarez, Stephen T.C. Wong, Kenneth Chang, Andrea Schietinger, Nasser Altorki, Vivek Mittal
Format: Article
Language:English
Published: Cambridge University Press 2021-03-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866121006300/type/journal_article

Internet

https://www.cambridge.org/core/product/identifier/S2059866121006300/type/journal_article

Similar Items