Identification of New Virulence Factors and Vaccine Candidates for Yersinia pestis

Identification of New Virulence Factors and Vaccine Candidates for Yersinia pestis

Earlier, we reported the identification of new virulence factors/mechanisms of Yersinia pestis using an in vivo signature-tagged mutagenesis (STM) screening approach. From this screen, the role of rbsA, which encodes an ATP-binding protein of ribose transport system, and vasK, an essential component...

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Bibliographic Details
Main Authors: Jourdan A. Andersson, Jian Sha, Tatiana E. Erova, Eric C. Fitts, Duraisamy Ponnusamy, Elena V. Kozlova, Michelle L. Kirtley, Ashok K. Chopra
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Yersinia pestis
mouse models of bubonic and pneumonic plague
type 6 secretion system and effectors
phagocytosis
intracellular survival
Online Access:http://journal.frontiersin.org/article/10.3389/fcimb.2017.00448/full

Internet

http://journal.frontiersin.org/article/10.3389/fcimb.2017.00448/full

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