Eosinophil-derived chemokine (hCCL15/23, mCCL6) interacts with CCR1 to promote eosinophilic airway inflammation

Abstract Eosinophils are terminally differentiated cells derived from hematopoietic stem cells (HSCs) in the bone marrow. Several studies have confirmed the effective roles of eosinophils in asthmatic airway pathogenesis. However, their regulatory functions have not been well elucidated. Here, incre...

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Bibliographic Details
Main Authors: Xufei Du, Fei Li, Chao Zhang, Na Li, Huaqiong Huang, Zhehua Shao, Min Zhang, Xueqin Zhan, Yicheng He, Zhenyu Ju, Wen Li, Zhihua Chen, Songmin Ying, Huahao Shen
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-021-00482-x