Intrathecal Methotrexate-Induced Necrotizing Myelopathy: A Case Report and Review of Histologic Features
Central nervous system (CNS) relapse of acute lymphoblastic leukemia (ALL) is associated with a poor prognosis. However, prophylactic measures, including intrathecal (IT) methotrexate, reduce the incidence of CNS relapse in these patients considerably. Unfortunately, IT methotrexate can cause severa...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2018-11-01
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Series: | Clinical Medicine Insights: Pathology |
Online Access: | https://doi.org/10.1177/1179555718809071 |