Intrathecal Methotrexate-Induced Necrotizing Myelopathy: A Case Report and Review of Histologic Features

Intrathecal Methotrexate-Induced Necrotizing Myelopathy: A Case Report and Review of Histologic Features

Central nervous system (CNS) relapse of acute lymphoblastic leukemia (ALL) is associated with a poor prognosis. However, prophylactic measures, including intrathecal (IT) methotrexate, reduce the incidence of CNS relapse in these patients considerably. Unfortunately, IT methotrexate can cause severa...

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Bibliographic Details
Main Authors:	Hamza Tariq, Andrea Gilbert, Francis E Sharkey
Format:	Article
Language:	English
Published:	SAGE Publishing 2018-11-01
Series:	Clinical Medicine Insights: Pathology
Online Access:	https://doi.org/10.1177/1179555718809071

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