Comparison of Myelotoxicity and Nephrotoxicity Between Daily Low-Dose Cisplatin With Concurrent Radiation and Cyclic High-Dose Cisplatin in Non-Small Cell Lung Cancer Patients

Comparison of Myelotoxicity and Nephrotoxicity Between Daily Low-Dose Cisplatin With Concurrent Radiation and Cyclic High-Dose Cisplatin in Non-Small Cell Lung Cancer Patients

AimAntineoplastic effect of cisplatin, the first line treatment in non-small cell lung cancer (NSCLC), is hindered by its nephrotoxicity and myelotoxicity. Both low-dose and high-dose regimens are used in the management of NSCLC. The aim of this study is to assess the risk on myelotoxicity and nephr...

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Bibliographic Details
Main Authors: Zulfan Zazuli, Renate Kos, Joris D. Veltman, Wilma Uyterlinde, Cristina Longo, Paul Baas, Rosalinde Masereeuw, Susanne J. H. Vijverberg, Anke-Hilse Maitland-van der Zee
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
cisplatin
low dose
radiotherapy
myelotoxicity
bone marrow suppression
nephrotoxicity
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00975/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00975/full

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