Ubiquitin-dependent proteolysis in yeast cells expressing neurotoxic proteins
Critically impaired protein degradation is discussed to contribute to neurodegenerative disorders, including Parkinson’s, Huntington’s, Alzheimer’s, and motor neuron diseases. Misfolded, aggregated, or surplus proteins are efficiently degraded via distinct protein degradation pathways, including the...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-03-01
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| Series: | Frontiers in Molecular Neuroscience |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnmol.2015.00008/full |