A fully human monoclonal antibody targeting Semaphorin 5A alleviates the progression of rheumatoid arthritis

A fully human monoclonal antibody targeting Semaphorin 5A alleviates the progression of rheumatoid arthritis

Rheumatoid arthritis (RA) is the most common chronic autoimmune disease worldwide. Although progress has been made in RA treatment in recent decades, remission cannot be effectively achieved for a considerable proportion of RA patients. Thus, novel potential targets for therapeutic strategies are ne...

Full description

Bibliographic Details
Main Authors: Yang Qin, Jiayi Jin, Jiani Zhang, Hui Wang, Li Liu, Yanwen Zhang, Sunwang Ling, Jinzhu Hu, Nuan Li, Jianguang Wang, Chen Lv, Xinyu Yang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Rheumatoid arthritis
Pannus
Angiogenesis
Monoclonal antibody
Phage display
Affinity maturation
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223014646

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223014646

Similar Items