3,3'-Diindolylmethane protects against cardiac hypertrophy via 5'-adenosine monophosphate-activated protein kinase-α2.

3,3'-Diindolylmethane protects against cardiac hypertrophy via 5'-adenosine monophosphate-activated protein kinase-α2.

PURPOSE: 3,3'-Diindolylmethane (DIM) is a natural component of cruciferous plants. It has strong antioxidant and anti-angiogenic effects and promotes the apoptosis of a variety of tumor cells. However, little is known about the critical role of DIM on cardiac hypertrophy. In the present study,...

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Bibliographic Details
Main Authors: Jing Zong, Wei Deng, Heng Zhou, Zhou-yan Bian, Jia Dai, Yuan Yuan, Jie-yu Zhang, Rui Zhang, Yan Zhang, Qing-qing Wu, Hai-peng Guo, Hong-liang Li, Qi-zhu Tang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3541184?pdf=render

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http://europepmc.org/articles/PMC3541184?pdf=render

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