No association between APOE genotype and lipid lowering with cognitive function in a randomized controlled trial of evolocumab

No association between APOE genotype and lipid lowering with cognitive function in a randomized controlled trial of evolocumab

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APOE encodes a cholesterol transporter, and the ε4 allele is associated with higher circulating cholesterol levels, ß-amyloid burden, and risk of Alzheimer’s disease. Prior studies demonstrated no significant differences in objective or subjective cognitive function for patients receiving the PCSK9...

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Bibliographic Details
Main Authors: Laura E. Korthauer, Robert P. Giugliano, Jianping Guo, Marc S. Sabatine, Peter Sever, Anthony Keech, Dan Atar, Christopher Kurtz, Christian T. Ruff, Francois Mach, Brian R. Ott
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000128/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9000128/?tool=EBI

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