New Derivatives of 3,4-Dihydroisoquinoline-3-carboxylic Acid with Free-Radical Scavenging, D-Amino Acid Oxidase, Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activity

New Derivatives of 3,4-Dihydroisoquinoline-3-carboxylic Acid with Free-Radical Scavenging, D-Amino Acid Oxidase, Acetylcholinesterase and Butyrylcholinesterase Inhibitory Activity

A series of 3,4-dihydroisoquinoline-3-carboxylic acid derivatives were synthesised and tested for their free-radical scavenging activity using 2,2-diphenyl-1-picrylhydrazyl radical (DPPH·), 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical (ABTS·+), superoxide anion radical (O2·−)...

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Bibliographic Details
Main Authors: Jolanta Solecka, Adam Guśpiel, Magdalena Postek, Joanna Ziemska, Robert Kawęcki, Katarzyna Łęczycka, Agnieszka Osior, Bartłomiej Pietrzak, Krzysztof Pypowski, Agata Wyrzykowska
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
free radicals
scavenger
DAAO
AChE
BuChE
inhibitor
3,4-dihydroisoquinoline
Online Access:http://www.mdpi.com/1420-3049/19/10/15866

Internet

http://www.mdpi.com/1420-3049/19/10/15866

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