Hydrolysis and transesterification of parabens in an aqueous solution in the presence of glycerol and boric acid

In a solution containing 0.067% methylparaben, 0.033% propylparaben, 3.4% glycerol and 2.0% boric acid, concentrations of both parabens, 4 hydroxybenzoic acid and 2,3-dihydroxypropyl 4-hydroxybenzoate were monitored for up to 68 months storage. 4-hydroxybenzoic acid is the main hydrolysis product of...

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Bibliographic Details
Main Authors: Oldrich Farsa, Jan Subert, Marie Marečkova
Format: Article
Language:English
Published: International Pharmaceutical Excipients Council 2016-11-01
Series:Journal of Excipients and Food Chemicals
Online Access:https://jefc.scholasticahq.com/article/1127-hydrolysis-and-transesterification-of-parabens-in-an-aqueous-solution-in-the-presence-of-glycerol-and-boric-acid