Numerical Simulation of the Behavior of Toroidal and Spheroidal Multicellular Aggregates in Microfluidic Devices with Microwell and U-Shaped Barrier

Numerical Simulation of the Behavior of Toroidal and Spheroidal Multicellular Aggregates in Microfluidic Devices with Microwell and U-Shaped Barrier

A microfluidic system provides an excellent platform for cellular studies. Most importantly, a three-dimensional (3D) cell culture model reconstructs more accurately the in vivo microenvironment of tissue. Accordingly, microfluidic 3D cell culture devices could be ideal candidates for in vitro cell...

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Bibliographic Details
Main Authors: Maryam Barisam, Mohammad Said Saidi, Navid Kashaninejad, Raja Vadivelu, Nam-Trung Nguyen
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:Micromachines
Subjects:
numerical simulation
microfluidics
oxygen/glucose distribution
shear stress
multicellular aggregates
toroid
spheroid
U-shaped barrier
microwell
bioreactor
Online Access:https://www.mdpi.com/2072-666X/8/12/358

Internet

https://www.mdpi.com/2072-666X/8/12/358

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