N-Acetylcysteine Amide against Aβ-Induced Alzheimer’s-like Pathology in Rats

N-Acetylcysteine Amide against Aβ-Induced Alzheimer’s-like Pathology in Rats

Oxidative stress with a depletion of glutathione is a key factor in the initiation and progression of Alzheimer’s disease (AD). N-Acetylcysteine (NAC), a glutathione precursor, provides neuroprotective effects in AD animal models. Its amide form, N-Acetylcysteine amide (NACA), has an extended bioava...

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Bibliographic Details
Main Authors: Ahmed Fareed Alkandari, Sampath Madhyastha, Muddanna S. Rao
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative stress
antioxidants
N-Acetylcysteine
N-Acetylcysteine amide
hippocampus
medial prefrontal cortex
Online Access:https://www.mdpi.com/1422-0067/24/16/12733

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https://www.mdpi.com/1422-0067/24/16/12733

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