Pre-epithelialized cryopreserved tracheal allograft for neo-trachea flap engineering

Background: Tracheal reconstruction presents a challenge because of the difficulty in maintaining the rigidity of the trachea to ensure an open lumen and in achieving an intact luminal lining that secretes mucus to protect against infection.Methods: On the basis of the finding that tracheal cartilag...

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Bibliographic Details
Main Authors: Ning Zeng, Youbai Chen, Yewen Wu, Mengqing Zang, Rene D. Largo, Edward I. Chang, Mark V. Schaverien, Peirong Yu, Qixu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1196521/full