A Speciation Study on the Perturbing Effects of Iron Chelators on the Homeostasis of Essential Metal Ions.

A number of reports have appeared in literature calling attention to the depletion of essential metal ions during chelation therapy on β-thalassaemia patients. We present a speciation study to determine how the iron chelators used in therapy interfere with the homeostatic equilibria of essential met...

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Bibliographic Details
Main Authors: Guido Crisponi, Valeria Marina Nurchi, Miriam Crespo-Alonso, Gavino Sanna, Maria Antonietta Zoroddu, Giancarla Alberti, Raffaela Biesuz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4508027?pdf=render