The Development of a Melt-Extruded Shellac Carrier for the Targeted Delivery of Probiotics to the Colon

Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved bioavailability. However, most commercial enteric or pH-responsive polymers are relativel...

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Bibliographic Details
Main Authors: Noel M. Gately, James E. Kennedy
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/9/4/38