Water extract from Ligusticum chuanxiong delays the aging of Saccharomyces cerevisiae via improving antioxidant activity
Ligusticum chuanxiong is a common traditional edible-medicinal herb that has various pharmacological activities. However, its effects on Saccharomyces cerevisiae (S. cerevisiae) remains unknown. In this study, we found that water extract of Ligusticum chuanxiong (abbreviated as WEL) exhibited excell...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-08-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844023062357 |
| _version_ | 1797732956053176320 |
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| author | Yinhui Yan Qianxing Zou Yueqi Zhou Huan He Wanguo Yu Haijun Yan Yi Yi Zaoya Zhao |
| author_facet | Yinhui Yan Qianxing Zou Yueqi Zhou Huan He Wanguo Yu Haijun Yan Yi Yi Zaoya Zhao |
| author_sort | Yinhui Yan |
| collection | DOAJ |
| description | Ligusticum chuanxiong is a common traditional edible-medicinal herb that has various pharmacological activities. However, its effects on Saccharomyces cerevisiae (S. cerevisiae) remains unknown. In this study, we found that water extract of Ligusticum chuanxiong (abbreviated as WEL) exhibited excellent free radical scavenging ability in-vitro. Moreover, WEL treatment could delay the aging of S. cerevisiae, an important food microorganism sensitive to reactive oxygen species (ROS) stress. Biochemical analyses revealed that WEL significantly increased the activity of antioxidant enzymes in S. cerevisiae, including superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR), as well as their gene expression. As a result, ROS level was significantly decreased and accompanied with the decline of malondialdehyde (MDA), which represented a state of low oxidative stress. The reduction of oxidative stress could elevate S. cerevisiae's ethanol fermentation efficiency. Taken together, WEL plays a protective role against S. cerevisiae aging via improving antioxidant activity. |
| first_indexed | 2024-03-12T12:21:02Z |
| format | Article |
| id | doaj.art-c74e16977ace4beebae7e4b32ff73088 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-12T12:21:02Z |
| publishDate | 2023-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-c74e16977ace4beebae7e4b32ff730882023-08-30T05:53:29ZengElsevierHeliyon2405-84402023-08-0198e19027Water extract from Ligusticum chuanxiong delays the aging of Saccharomyces cerevisiae via improving antioxidant activityYinhui Yan0Qianxing Zou1Yueqi Zhou2Huan He3Wanguo Yu4Haijun Yan5Yi Yi6Zaoya Zhao7Guangxi Key Laboratory of Green Processing of Sugar Resources, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545006, PR ChinaDepartment of Reproductive Medicine, Liuzhou People's Hospital affiliated to Guangxi Medical University, Liuzhou, 545006, PR ChinaGuangxi Key Laboratory of Green Processing of Sugar Resources, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545006, PR ChinaGuangxi Key Laboratory of Green Processing of Sugar Resources, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545006, PR ChinaGuangxi Key Laboratory of Green Processing of Sugar Resources, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545006, PR ChinaState Key Laboratory of Biocontrol, Institute of Aquatic Economic Animals and Guangdong Province Key Laboratory for Aquatic Economic Animals, South China Sea Bio-Resource Exploitation and Collaborative Innovation Center, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510006, PR ChinaGuangxi Key Laboratory of Green Processing of Sugar Resources, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545006, PR China; Corresponding author.Guangxi Key Laboratory of Green Processing of Sugar Resources, College of Biological and Chemical Engineering, Guangxi University of Science and Technology, Liuzhou 545006, PR China; Corresponding author.Ligusticum chuanxiong is a common traditional edible-medicinal herb that has various pharmacological activities. However, its effects on Saccharomyces cerevisiae (S. cerevisiae) remains unknown. In this study, we found that water extract of Ligusticum chuanxiong (abbreviated as WEL) exhibited excellent free radical scavenging ability in-vitro. Moreover, WEL treatment could delay the aging of S. cerevisiae, an important food microorganism sensitive to reactive oxygen species (ROS) stress. Biochemical analyses revealed that WEL significantly increased the activity of antioxidant enzymes in S. cerevisiae, including superoxide dismutase (SOD), catalase (CAT) and glutathione reductase (GR), as well as their gene expression. As a result, ROS level was significantly decreased and accompanied with the decline of malondialdehyde (MDA), which represented a state of low oxidative stress. The reduction of oxidative stress could elevate S. cerevisiae's ethanol fermentation efficiency. Taken together, WEL plays a protective role against S. cerevisiae aging via improving antioxidant activity.http://www.sciencedirect.com/science/article/pii/S2405844023062357Ligusticum chuanxiongSaccharomyces cerevisiaeReactive oxygen speciesAntioxidant activityEthanol fermentation |
| spellingShingle | Yinhui Yan Qianxing Zou Yueqi Zhou Huan He Wanguo Yu Haijun Yan Yi Yi Zaoya Zhao Water extract from Ligusticum chuanxiong delays the aging of Saccharomyces cerevisiae via improving antioxidant activity Heliyon Ligusticum chuanxiong Saccharomyces cerevisiae Reactive oxygen species Antioxidant activity Ethanol fermentation |
| title | Water extract from Ligusticum chuanxiong delays the aging of Saccharomyces cerevisiae via improving antioxidant activity |
| title_full | Water extract from Ligusticum chuanxiong delays the aging of Saccharomyces cerevisiae via improving antioxidant activity |
| title_fullStr | Water extract from Ligusticum chuanxiong delays the aging of Saccharomyces cerevisiae via improving antioxidant activity |
| title_full_unstemmed | Water extract from Ligusticum chuanxiong delays the aging of Saccharomyces cerevisiae via improving antioxidant activity |
| title_short | Water extract from Ligusticum chuanxiong delays the aging of Saccharomyces cerevisiae via improving antioxidant activity |
| title_sort | water extract from ligusticum chuanxiong delays the aging of saccharomyces cerevisiae via improving antioxidant activity |
| topic | Ligusticum chuanxiong Saccharomyces cerevisiae Reactive oxygen species Antioxidant activity Ethanol fermentation |
| url | http://www.sciencedirect.com/science/article/pii/S2405844023062357 |
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