STRONG: metagenomics strain resolution on assembly graphs

STRONG: metagenomics strain resolution on assembly graphs

Abstract We introduce STrain Resolution ON assembly Graphs (STRONG), which identifies strains de novo, from multiple metagenome samples. STRONG performs coassembly, and binning into metagenome assembled genomes (MAGs), and stores the coassembly graph prior to variant simplification. This enables the...

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Bibliographic Details
Main Authors: Christopher Quince, Sergey Nurk, Sebastien Raguideau, Robert James, Orkun S. Soyer, J. Kimberly Summers, Antoine Limasset, A. Murat Eren, Rayan Chikhi, Aaron E. Darling
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Genome Biology
Subjects:
Microbiome
Metagenome
Strains
Bayesian
Microbial community
Assembly graph
Online Access:https://doi.org/10.1186/s13059-021-02419-7

Internet

https://doi.org/10.1186/s13059-021-02419-7

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