Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: A novel candidate SNP approach

Leveraging ethnic group incidence variation to investigate genetic susceptibility to glioma: A novel candidate SNP approach

Objectives: Using a novel candidate SNP approach, we aimed to identify a possible genetic basis for the higher glioma incidence in Whites relative to East Asians and African-Americans. Methods: We hypothesized that genetic regions containing SNPs with extreme differences in allele frequencies acros...

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Bibliographic Details
Main Authors: Daniel Ian Jacobs, Kyle M. Walsh, Margaret eWrensch, John eWiencke, Robert eJenkins, Richard eHoulston, Melissa eBondy, Matthias eSimon, Marc eSanson, Konstantinos eGousias, Johannes eSchramm, Marianne eLabussiere, Anna Luisa eDi Stefano, H-Erich eWichmann, Martina eMüller-Nurasyid, Stefan eSchreiber, Andre eFranke, Susanne eMoebus, Lewin eEisele, Andrew eDeWan, Robert eDubrow
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Genetics
Subjects:
Glioma
race
admixture
Ancestry informative markers
ethnicity
candidate SNP association study
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00203/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00203/full

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