Clinical analysis of 82 cases of acute promyelocytic leukemia with PML-RARα short isoform in children and adults

Clinical analysis of 82 cases of acute promyelocytic leukemia with PML-RARα short isoform in children and adults

BackgroundAcute promyelocytic leukemia (APL) with PML/RARα fusion gene is a distinct variant of acute myeloid leukemia. According to the different break sites of the PML gene, there are three transcripts: Long (bcr1), Variant (bcr2) and Short (bcr3).MethodsWe retrospectively analyzed 82 APL cases wi...

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Bibliographic Details
Main Authors: Qiaolin Huang, Yicheng Zhang, Miao Zheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Oncology
Subjects:
acute promyelocytic leukemia
PML-RARα short isoform
bcr3 isoform
clinical features
gene mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1342671/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1342671/full

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