Is L-Glutamate Toxic to Neurons and Thereby Contributes to Neuronal Loss and Neurodegeneration? A Systematic Review

L-glutamate (L-Glu) is a nonessential amino acid, but an extensively utilised excitatory neurotransmitter with critical roles in normal brain function. Aberrant accumulation of L-Glu has been linked to neurotoxicity and neurodegeneration. To investigate this further, we systematically reviewed the l...

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Bibliographic Details
Main Authors: Maryam N. AL-Nasser, Ian R. Mellor, Wayne G. Carter
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/12/5/577