Biosynthesis of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) From Glucose by Escherichia coli Through Butyryl-CoA Formation Driven by Ccr-Emd Combination

Biosynthesis of Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) From Glucose by Escherichia coli Through Butyryl-CoA Formation Driven by Ccr-Emd Combination

Poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] [P(3HB-co-3HHx)] is a practical kind of bacterial polyhydroxyalkanoates (PHAs). A previous study has established an artificial pathway for the biosynthesis of P(3HB-co-3HHx) from structurally unrelated sugars in Ralstonia eutropha, in which croto...

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Bibliographic Details
Main Authors: Shu Saito, Ryu Imai, Yuki Miyahara, Mari Nakagawa, Izumi Orita, Takeharu Tsuge, Toshiaki Fukui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
metabolic engineering
poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)
polyhydroxyalkanoates
Escherichia coli
reverse β-oxidation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.888973/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2022.888973/full

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