Cohesin-independent STAG proteins interact with RNA and R-loops and promote complex loading

Cohesin-independent STAG proteins interact with RNA and R-loops and promote complex loading

Most studies of cohesin function consider the Stromalin Antigen (STAG/SA) proteins as core complex members given their ubiquitous interaction with the cohesin ring. Here, we provide functional data to support the notion that the SA subunit is not a mere passenger in this structure, but instead plays...

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Bibliographic Details
Main Authors: Hayley Porter, Yang Li, Maria Victoria Neguembor, Manuel Beltran, Wazeer Varsally, Laura Martin, Manuel Tavares Cornejo, Dubravka Pezić, Amandeep Bhamra, Silvia Surinova, Richard G Jenner, Maria Pia Cosma, Suzana Hadjur
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-04-01
Series:eLife
Subjects:
STAG proteins
RNA binding proteins
R-loops
cohesin loading
Online Access:https://elifesciences.org/articles/79386

Internet

https://elifesciences.org/articles/79386

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